Ku-Lung Hsu: search on Z-Library

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1

Chemoproteomic discovery of a ritanserin-targeted kinase network mediating apoptotic cell death of lung tumor cells

Campbell, Sean T, Franks, Caroline E, Borne, Adam L, Shin, Myungsun, Zhang, Liuzhi, Hsu, Ku-Lung

Journal:

Molecular Pharmacology

Year:

2018

Language:

english

File:

PDF, 2.84 MB

english, 2018

2

Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons

Baggelaar, Marc P., Chameau, Pascal J. P., Kantae, Vasudev, Hummel, Jessica, Hsu, Ku-Lung, Janssen, Freek, van der Wel, Tom, Soethoudt, Marjolein, Deng, Hui, den Dulk, Hans, Allarà, Marco, Florea, Bog

Journal:

Journal of the American Chemical Society

Year:

2015

Language:

english

File:

PDF, 2.69 MB

english, 2015

3

Automated Spatially Targeted Optical Micro Proteomics (autoSTOMP) to Determine Protein Complexity of Subcellular Structures

Yin, Bocheng, Mendez, Roberto, Zhao, Xiao-Yu, Rakhit, Rishi, Hsu, Ku-Lung, Ewald, Sarah E

Journal:

Analytical Chemistry

Year:

2019

File:

PDF, 762 KB

2019

4

Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer

Kohnz, Rebecca A., Mulvihill, Melinda M., Chang, Jae Won, Hsu, Ku-Lung, Sorrentino, Antonio, Cravatt, Benjamin F., Bandyopadhyay, Sourav, Goga, Andrei, Nomura, Daniel K.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 2.53 MB

english, 2015

5

Re-examining the potential of targeting ABHD6 in multiple sclerosis: Efficacy of systemic and peripherally restricted inhibitors in experimental autoimmune encephalomyelitis

Manterola, Andrea, Bernal-Chico, Ana, Cipriani, Raffaela, Ruiz, Asier, Pérez-Samartín, Alberto, Moreno-Rodríguez, Marta, Hsu, Ku-Lung, Cravatt, Benjamin, Brown, J. Mark, Rodríguez-Puertas, Rafael, Mat

Journal:

Neuropharmacology

Year:

2018

Language:

english

File:

PDF, 1.55 MB

english, 2018

6

Development and Optimization of Piperidyl-1,2,3-Triazole Ureas as Selective Chemical Probes of Endocannabinoid Biosynthesis

Hsu, Ku-Lung, Tsuboi, Katsunori, Whitby, Landon R., Speers, Anna E., Pugh, Holly, Inloes, Jordon, Cravatt, Benjamin F.

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.78 MB

english, 2013

7

Lacritin proteoforms prevent tear film collapse and maintain epithelial homeostasis

Georgiev, Georgi A, Sharifian Gh, Mohammad, Romano, Jeff, Dias Teixeira, Karina L, Struble, Craig, Ryan, Denise S., Sia, Rose K, Kitt, Jay P, Harris, Joel M, Hsu, Ku-Lung, Libby, Adam, Odrich, Marc G,

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 4.76 MB

2020

8

Fabrication of an Oriented Lectin Microarray

Daniel C. Propheter , Ku-Lung Hsu , Lara K. Mahal

Journal:

Year:

2010

Language:

english

File:

PDF, 512 KB

english, 2010

9

Sweet tasting chips: microarray-based analysis of glycans

Ku-Lung Hsu, Lara K Mahal

Journal:

Current Opinion in Chemical Biology

Year:

2009

Language:

english

File:

PDF, 733 KB

english, 2009

10

Analyzing the dynamic bacterial glycome with a lectin microarray approach

Hsu, Ku-Lung, Pilobello, Kanoelani T, Mahal, Lara K

Journal:

Nature Chemical Biology

Year:

2006

Language:

english

File:

PDF, 319 KB

english, 2006

11

Lipid-metabolizing serine hydrolases in the mammalian central nervous system: endocannabinoids and beyond

Shin, Myungsun, Ware, Timothy B., Lee, Hyeon-Cheol, Hsu, Ku-Lung

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2018

Language:

english

File:

PDF, 1.06 MB

english, 2018

12

Evaluation of different drug classes on transient sciatic nerve injury-depressed marble burying in mice

Wilkerson, Jenny L, Curry, Zachary A, Kinlow, Pamela D, Mason, Brittany L, Hsu, Ku-Lung, van der Stelt, Mario, Cravatt, Benjamin F, Lichtman, Aron H

Journal:

Year:

2018

Language:

english

File:

PDF, 2.33 MB

english, 2018

13

Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure

Buczynski, Matthew W., Herman, Melissa A., Hsu, Ku-Lung, Natividad, Luis A., Irimia, Cristina, Polis, Ilham Y., Pugh, Holly, Chang, Jae Won, Niphakis, Micah J., Cravatt, Benjamin F., Roberto, Marisa,

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1.36 MB

english, 2016

14

The Ligand Binding Landscape of Diacylglycerol Kinases

Franks, Caroline E., Campbell, Sean T., Purow, Benjamin W., Harris, Thurl E., Hsu, Ku-Lung

Journal:

Cell Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.77 MB

english, 2017

15

Deconstructing Lipid Kinase Inhibitors by Chemical Proteomics

McCloud, Rebecca L., Franks, Caroline E., Campbell, Sean T., Purow, Benjamin W., Harris, Thurl E., Hsu, Ku-Lung

Journal:

Year:

2017

Language:

english

File:

PDF, 2.43 MB

english, 2017

16

A lectin microarray approach for the rapid analysis of bacterial glycans

Hsu, Ku-Lung, Mahal, Lara K

Journal:

Nature Protocols

Year:

2006

Language:

english

File:

PDF, 179 KB

english, 2006

17

Discovery and Optimization of Piperidyl-1,2,3-Triazole Ureas as Potent, Selective, and in Vivo-Active Inhibitors of α/β-Hydrolase Domain Containing 6 (ABHD6)

Hsu, Ku-Lung, Tsuboi, Katsunori, Chang, Jae Won, Whitby, Landon R., Speers, Anna E., Pugh, Holly, Cravatt, Benjamin F.

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.57 MB

english, 2013

18

Regulation of calcium release from the endoplasmic reticulum by the serine hydrolase ABHD2

Yun, Bogeon, Lee, HeeJung, Powell, Roger, Reisdorph, Nichole, Ewing, Heather, Gelb, Michael H., Hsu, Ku-Lung, Cravatt, Benjamin F., Leslie, Christina C.

Journal:

Biochemical and Biophysical Research Communications

Year:

2017

Language:

english

File:

PDF, 1.68 MB

english, 2017

19

Identification of the Major Prostaglandin Glycerol Ester Hydrolase in Human Cancer Cells

Manna, Joseph D., Wepy, James A., Hsu, Ku-Lung, Chang, Jae Won, Cravatt, Benjamin F., Marnett, Lawrence J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.00 MB

english, 2014

20

ABHD6 Blockade Exerts Antiepileptic Activity in PTZ-Induced Seizures and in Spontaneous Seizures in R6/2 Mice

Naydenov, Alipi V., Horne, Eric A., Cheah, Christine S., Swinney, Katie, Hsu, Ku-Lung, Cao, Jessica K., Marrs, William R., Blankman, Jacqueline L., Tu, Sarah, Cherry, Allison E., Fung, Susan, Wen, And

Journal:

Year:

2014

Language:

english

File:

PDF, 2.04 MB

english, 2014

21

Automated Spatially Targeted Optical Micro Proteomics (autoSTOMP) to Determine Protein Complexity of Subcellular Structures

Yin, Bocheng, Mendez, Roberto, Zhao, Xiao-Yu, Rakhit, Rishi, Hsu, Ku-Lung, Ewald, Sarah E

Journal:

Analytical Chemistry

Year:

2019

Language:

english

File:

PDF, 762 KB

english, 2019

22

Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models

Grim, Travis W., Ghosh, Sudeshna, Hsu, Ku-Lung, Cravatt, Benjamin F., Kinsey, Steven G., Lichtman, Aron H.

Journal:

Pharmacology Biochemistry and Behavior

Year:

2014

Language:

english

File:

PDF, 750 KB

english, 2014

23

DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses

Hsu, Ku-Lung, Tsuboi, Katsunori, Adibekian, Alexander, Pugh, Holly, Masuda, Kim, Cravatt, Benjamin F

Journal:

Nature Chemical Biology

Year:

2012

Language:

english

File:

PDF, 790 KB

english, 2012

24

Monoacylglycerol lipase inhibitors reverse paclitaxel-induced nociceptive behavior and proinflammatory markers in a mouse model of chemotherapy-induced neuropathy

Curry, Zachary, Wilkerson, Jenny, Bagdas, Deniz, Kyte, Sarah, Patel, Nipa, Donvito, Giulia, Mustafa, Mohammed A, Poklis, Justin, Niphakis, Micah, Hsu, Ku-Lung, Cravatt, Benjamin F., Gewirtz, David A.,

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2018

Language:

english

File:

PDF, 1.52 MB

english, 2018

25

Selective inhibitors and tailored activity probes for lipoprotein-associated phospholipase A2

Nagano, Joseph M.G., Hsu, Ku-Lung, Whitby, Landon R., Niphakis, Micah J., Speers, Anna E., Brown, Steven J., Spicer, Timothy, Fernandez-Vega, Virneliz, Ferguson, Jill, Hodder, Peter, Srinivasan, Prabh

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.23 MB

english, 2013

26

Click-generated triazole ureas as ultrapotent in vivo–active serine hydrolase inhibitors

Adibekian, Alexander, Martin, Brent R, Wang, Chu, Hsu, Ku-Lung, Bachovchin, Daniel A, Niessen, Sherry, Hoover, Heather, Cravatt, Benjamin F

Journal:

Nature Chemical Biology

Year:

2012

Language:

english

File:

PDF, 58 KB

english, 2012

27

A simple strategy for the creation of a recombinant lectin microarray

Hsu, Ku-Lung, Gildersleeve, Jeffrey C., Mahal, Lara K.

Journal:

Molecular BioSystems

Year:

2008

Language:

english

File:

PDF, 1.05 MB

english, 2008

28

Click-generated triazole ureas as ultrapotent in vivo–active serine hydrolase inhibitors

Adibekian, Alexander, Martin, Brent R, Wang, Chu, Hsu, Ku-Lung, Bachovchin, Daniel A, Niessen, Sherry, Hoover, Heather, Cravatt, Benjamin F

Journal:

Nature Chemical Biology

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

29

Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes

Dominguez, Eduardo, Galmozzi, Andrea, Chang, Jae Won, Hsu, Ku-Lung, Pawlak, Joanna, Li, Weiwei, Godio, Cristina, Thomas, Jason, Partida, David, Niessen, Sherry, O'Brien, Paul E, Russell, Aaron P, Watt

Journal:

Nature Chemical Biology

Year:

2013

Language:

english

File:

PDF, 2.47 MB

english, 2013

30

Diacylglycerol Lipase-β Is Required for TNF-α Response but Not CD8+ T Cell Priming Capacity of Dendritic Cells

Shin, Myungsun, Buckner, Andrew, Prince, Jessica, Bullock, Timothy N.J., Hsu, Ku-Lung

Journal:

Cell Chemical Biology

Year:

2019

Language:

english

File:

PDF, 1.96 MB

english, 2019

31

Competitive Activity-Based Protein Profiling Identifies Aza-β-Lactams as a Versatile Chemotype for Serine Hydrolase Inhibition

Zuhl, Andrea M., Mohr, Justin T., Bachovchin, Daniel A., Niessen, Sherry, Hsu, Ku-Lung, Berlin, Jacob M., Dochnahl, Maximilian, López-Alberca, María P., Fu, Gregory C., Cravatt, Benjamin F.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 2.44 MB

english, 2012

32

Next-Generation Cell-Active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase

Lazo, John S., Blanco, Isabella K., Tasker, Nikhil R., Rastelli, Ettore J., Burnett, James C., Garrott, Sharon R., Hart, Duncan J., McCloud, Rebecca L., Hsu, Ku-Lung, Wipf, Peter, Sharlow, Elizabeth R

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2019

File:

PDF, 980 KB

2019

33

DAGL-Beta Functions as a PUFA-Specific Triacylglycerol Lipase in Macrophages

Shin, Myungsun, Ware, Timothy B., Hsu, Ku-Lung

Journal:

Cell Chemical Biology

Year:

2020

Language:

english

File:

PDF, 1.88 MB

english, 2020

34

Liganding Functional Tyrosine Sites on Proteins Using SulfurâTriazole Exchange Chemistry

Brulet, Jeffrey W., Borne, Adam L., Yuan, Kun, Libby, Adam H., Hsu, Ku-Lung

Journal:

Journal of the American Chemical Society

Year:

2020

File:

PDF, 1.75 MB

2020

35

Confirming Target Engagement for Reversible Inhibitors in Vivo by Kinetically Tuned Activity-Based Probes

Adibekian, Alexander, Martin, Brent R., Chang, Jae Won, Hsu, Ku-Lung, Tsuboi, Katsunori, Bachovchin, Daniel A., Speers, Anna E., Brown, Steven J., Spicer, Timothy, Fernandez-Vega, Virneliz, Ferguson,

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 4.07 MB

english, 2012

36

Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure

Buczynski, Matthew W., Herman, Melissa A., Hsu, Ku-Lung, Natividad, Luis A., Irimia, Cristina, Polis, Ilham Y., Pugh, Holly, Chang, Jae Won, Niphakis, Micah J., Cravatt, Benjamin F., Roberto, Marisa,

Journal:

Year:

2017

Language:

english

File:

PDF, 57 KB

english, 2017

37

Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo

Shin, Myungsun, Snyder, Helena W., Donvito, Giulia, Schurman, Lesley D., Fox, Todd E., Lichtman, Aron H., Kester, Mark, Hsu, Ku-Lung

Journal:

Molecular Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 2.51 MB

english, 2017

38

Isoform-selective activity-based profiling of ERK signaling

Shin, Myungsun, Franks, Caroline E., Hsu, Ku-Lung

Journal:

Chemical Science

Year:

2018

Language:

english

File:

PDF, 3.66 MB

english, 2018

39

[Current Topics in Microbiology and Immunology] Activity-Based Protein Profiling Volume 420 ||

Cravatt, Benjamin F., Hsu, Ku-Lung, Weerapana, Eranthie

Year:

2019

File:

PDF, 10.60 MB

2019

40

Reprogramming fatty acyl specificity of lipid kinases via C1 domain engineering

Ware, Timothy B., Franks, Caroline E., Granade, Mitchell E., Zhang, Mingxing, Kim, Kee-Beom, Park, Kwon-Sik, Gahlmann, Andreas, Harris, Thurl E., Hsu, Ku-Lung

Journal:

Nature Chemical Biology

Year:

2020

File:

PDF, 4.22 MB

2020

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